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. 2013 Dec 4;34(3):389–396. doi: 10.1038/jcbfm.2013.220

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Copyright © 2014 International Society for Cerebral Blood Flow & Metabolism, Inc.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/

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Changes in the indicated physiologic parameters and quantitative gCBF during moderate, steady-state cycling exercise. (A) Time course of the indicated physiologic parameters. Boxes indicate the transmission scan (T), emission scans of the Rest, Ex1, and Ex2 periods. Injection time of oxygen-15-labeled water for the first positron emission tomography (PET) scan was defined as Time 0. Each data point represents the mean±s.d. of a 1-minute epoch (n=10). (B) Individual results for arterial CO₂ (P_aCO₂) and global cerebral blood flow (gCBF) at Rest, Ex1, and Ex2. Each symbol represents an individual subject. DBP, diastolic blood pressure; HR, heart rate; MBP, mean blood pressure; SBP, systolic blood pressure; VO₂, pulmonary oxygen consumption.