Table 1. Physiologic parameters measured at Rest and during exercise.
| Rest | Ex1 | Ex2 | |
|---|---|---|---|
| Heart rate (b.p.m.) | 60±5 | 96±2*** | 104±9*** |
| Cardiac output (L/minute) | 3.8±0.7 | 7.3±1.4*** | 8.3±1.5***,† |
| VO2 (mL/min per kg) | 5.4±1.2 | 18.6±4.4*** | 18.8±4.2*** |
| Systolic blood pressure (mm Hg) | 123±20 | 133±22* | 135±20** |
| Diastolic blood pressure (mm Hg) | 74±13 | 68±9 | 64±9* |
| Mean blood pressure (mm Hg) | 86±14 | 87±9.4 | 86±10 |
| PETCO2 (mm Hg) | 37.1±2.1 | 43.9±3.8*** | 42.2±4.0*** |
| PaCO2 (mm Hg) | 36.9±2.6 | 38.9±2.9** | 39.0±3.2* |
PaCO2, arterial tension of carbon dioxide; PETCO2, end-tidal partial pressure of carbon dioxide; VO2, pulmonary oxygen uptake.
Values are shown as means±s.d. (n=10).
With the exception of PaCO2, the data were averaged over 2 minutes of the PET scan. Significance of difference from Rest: *P<0.05, **P<0.01, ***P<0.0001. Significance of difference from Ex1: †P<0.05.