Table 1. Inflammasomes in the CNS and their activators.

Inflammasome	Activators	Components	References
NLRP1	High extracellular potassium	NLRP1, caspase-1, caspase-11, ASC, XIAP	de Rivero Vaccari et al.,6 Silverman et al.18
NLRP2	ATP	NLRP2, caspase-1, ASC	Minkiewicz et al.7
NLRP3	ATP, β-amyloid	NLRP3, caspase-1, ASC	Halle et al.,8 Mariathasan et al.60
AIM2	DNA	AIM2, caspase-1, ASC	Adamczak SE et al.11

Abbreviations: CNS, central nervous system; XIAP, X-linked inhibitor of apoptosis protein.