Table 1. List of the Dispersive (δd), Polar (δp), H-Bonding (δh) Hansen-Solubility Parameters (HSPs for solvents,108 mean value for SiOx22 and Clotrimazole27) Together with the Solubility Parameter Distance for Solvent–Clotrimazole Combinationsa.
| HSP |
Ra |
cryst |
||||||
|---|---|---|---|---|---|---|---|---|
| mater | δd | δp | δh | Clot. | SiOx | pv [torr] | dc | va |
| H2O | 15.5 | 16.0 | 42.3 | 41.7 | 23.3 | 23.727 | na | + |
| MeOH | 15.1 | 12.3 | 22.3 | 24.0 | 10.7 | 126.927 | – | + |
| EtOH | 15.8 | 8.8 | 19.4 | 19.9 | 13.4 | 58.827 | – | + |
| IPA | 15.8 | 6.1 | 16.4 | 17.2 | 16.5 | 43.727 | – | + |
| XYL | 17.6 | 1.0 | 3.1 | 9.4 | 27.0 | 8.327 | + | + |
| TOL | 18.0 | 1.4 | 2.0 | 8.8 | 27.4 | 28.427 | + | + |
| DMK | 15.2 | 7.4 | 4.8 | 14.0 | 21.4 | 229.527 | – | + |
| MeCN | 15.3 | 18.0 | 6.1 | 19.5 | 14.9 | 91.227 | – | + |
| THF | 16.8 | 5.7 | 8.0 | 11.1 | 20.2 | 162.227 | – | – |
| SiOx | 17 | 22 | 20 | 25.7 | 0.0 | – | ||
| Clot. | 22.0 | 3.9 | 4.6 | 0.0 | 25.8 | – | ||
a
Additionally, the viscosity (η) and the vapor pressure (pv) are listed. Last two columns indicate if crystallization was observed (+) or was not (−) for the drop cast (dc) and vapor annealed (va) samples.