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. 2014 Feb 18;111(9):E866–E875. doi: 10.1073/pnas.1319196111

Table 1.

Potentially deleted genes according to copy number (CNV), transcript level (abundance [reads per kilobase per million reads (RPKM)] and regulation [log2FC]), and median protein staining level in malignant and healthy renal tissue

Gene Gene locus Mean CNV amplitude CNV frequency (%) RPKM log2FC Median staining renal cancers Staining kidney cells in tubules Enzymatic activity
ABHD5 3p21.31 −0.236 81.15 2.69 −0.94 Negative Moderate 1-acylglycerol-3-phosphate O-acyltransferase
CHDH 3p21.1 −0.227 78.28 9.54 −1.05 Negative Strong Choline dehydrogenase
GPD1L 3p22.3 −0.234 80.94 4.96 −0.83 Negative Moderate Glycerol-3-phosphate dehydrogenase
IMPDH2 3p21.31 −0.236 81.15 8.19 −0.68 Negative Moderate IMP dehydrogenase
PDHB 3p14.3 −0.216 74.80 4.35 −1.30 Negative Strong Pyruvate dehydrogenase