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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Transl Stroke Res. 2013 Aug 6;5(1):109–117. doi: 10.1007/s12975-013-0276-z

Figure 3.

Figure 3

Post-treatment with PAME, SAME, or Solutol HS 15 after 2 hrs of MCAO decreases total rat brain infarct volume. Post-treatment with PAME (0.02 mg/kg, IV), SAME (0.02 mg/kg, IV), or Solutol HS 15 (2 ml/kg, IV) decreased ipsilateral hemisphere volume as compared to saline (vehicle for Solutol HS 15), DMSO [partial vehicle for (12-HS), PAME, or SAME], and 12-HS (negative control). TTC-treated brain slices were scanned and analyzed (Image J software) at the ipsilateral hemisphere. The percent of brain infarct volume is depicted in white and tabulated in panel (A) and the total brain infarct volume (expressed in mm3) is presented in (B). Representative images are shown below each bar graph corresponding to their relative drug treatment (A) (n = 6-8, * p ≤ 0.05).