Table 2. Asphyxial cardiac arrest physiological parameters.
Physiological parameters such as body weight, pH, PCO2, PO2, MABP, and blood glucose were measured to ensure consistency of the animals within and between groups.
| Groups | Variable | Before ACA | 30 mins after ACA | 24 hrs after ACA |
|---|---|---|---|---|
| PAME (0.02 mg/kg, IV) (n = 6) |
Body wt (g) | 333.5 ± 9.61 | – | – |
| pH | 7.46 ± 0.02 | 7.47 ± 0.04 | 7.40 ± 0.03 | |
| PCO2 (mm Hg) | 34.4 ± 1.3 | 33.1 ± 2.1 | 39.9 ± 2.4 | |
| PO2 (mm Hg) | 112.8 ± 15.7 | 224.7 ± 31.9* | 113.7 ± 6.3 | |
| MABP (mm Hg) | 102.7 ± 4.8 | 91.3 ± 3.05 | 90.5 ± 1.2 | |
| Glucose (mg/dL) | 118 ± 10 | |||
| SAME (0.02 mg/kg, IV) (n = 3) |
Body wt (g) | 313.3 ± 9.61 | – | – |
| pH | 7.48 ± 0.03 | 7.51 ± 0.04 | 7.48 ± 0.01 | |
| PCO2 (mm Hg) | 33.8 ± 2.2 | 31.2 ± 3.4 | 33.4 ± 0.7 | |
| PO2 (mm Hg) | 108.2 ± 12.5 | 380 ± 67* | 125 ± 7 | |
| MABP (mm Hg) | 103.3 ± 5.2 | 99.3 ± 6.44 | 93.3 ± 1.9 | |
| Glucose (mg/dL) | 103 ± 7 |
*
denotes significant difference from before and 24 hrs after ACA due to the delivery of 100 % O2 upon resuscitation to achieve ROSC. Values are mean ± S.E.M. ACA, asphyxial cardiac arrest; MABP, mean arterial blood pressure.