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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Future Med Chem. 2013 Oct;5(15):1763–1776. doi: 10.4155/fmc.13.108

Table 2.

Microsomal stability screen data summary.

Compound Concentration
(µM)
Mean remaining Comments
Parent comp (%) Parent comp (%)
(+)NADPH (−)NADPH
Verapamil 1 5.6 113 High metabolized control
Warfarin 1 83.9 118 Low metabolized control
1 1 5.1 112
4 1 90.2 115
8 1 91.6 120
10 1 1.0 108