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. 2014 Mar 7;9(3):e90614. doi: 10.1371/journal.pone.0090614

Table 4. Mortality by HIV status and potential explanatory factors.

HIV-uninfected HIV infected
Factor Level n Deaths Mortality rate per 100 pyo (95% c.i.) n deaths Mortality rate per 100 pyo (95% c.i.)
Overall 32 11 19.7 (10.9; 35.5) 64 41 46.9 (34.6; 63.7)
Age <30 20 5 13.2 (5.5; 31.9) 28 17 40.1 (24.9; 64.5)
(years) 30–40 5 3 43.0 (13.9; 133) 26 19 70.0 (44.7; 109)
>40 7 3 26.7 (8.6; 82.7) 10 5 28.1 (11.7; 67.4)
Sex Female 7 2 13.0 (3.2; 51.9) 39 25 44.8 (30.3; 66.3)
Male 25 9 22.2 (11.6; 42.7) 25 16 50.7 (31.1; 82.8)
BMI1 (kg/m2) ≤15 8 2 15.2 (3.8; 61.0) 17 10 33.9 (18.2; 63.0)
>15–18.5 12 4 19.3 (7.2; 51.4) 34 20 41.7 (26.9; 64.7)
>18.5 12 5 22.7 (9.4; 54.5) 12 10 111 (59.8; 206)
Karnofsky Score 70 + 20 2 4.6 (1.1; 18.4) 36 16 26.3 (16.1; 42.9)
≤ 60 12 9 72.6 (37.8; 139) 28 25 94.6 (63.9; 140)
Resistance Status Sens HR 29 10 19.6 (10.6; 36.5) 60 38 45.2 (32.9; 62.1)
Res H/R or both 3 1 20.0 (2.8; 142) 4 3 91.2 (29.4; 282)
Sputum smear grade 1+ or 2+ 6 1 10.8 (1.5; 76.3) 18 11 41.2 (22.8; 74.3)
3+ 5 1 8.0 (1.1; 56.6) 11 9 72.0 (37.5; 138)
4+ 21 9 26.4 (13.7; 50.8) 35 21 43.6 (28.5; 66.9)
Extent of disease on chest X-ray Norm/Min 0 0 - 21 14 64.6 (38.3; 109)
Moderate 3 1 19.4 (2.7; 138) 15 9 36.1 (18.8; 69.4)
Severe 28 10 21.2 (11.4; 39.5) 27 17 43.8 (27.2; 70.4)
Cavitation No 4 2 38.7 (9.7; 154) 49 31 43.9 (30.9; 62.4)
Yes 27 9 19.1 (10.0; 36.8) 12 8 66.7 (33.3; 133)
Duration of TB symptoms <3 months 11 3 14.7 (4.7; 45.5) 40 27 49.9 (34.2; 72.8)
3–6 months 14 8 44.1 (22.1; 88.2) 20 12 48.7 (27.7; 85.7)
> 6 months 7 0 0 4 2 23.3 (5.8; 93.1)
DTP ≥7 days 14 2 5.9 (1.5; 23.6) 32 19 40.7 (26.0; 63.8)
< 7 days 18 9 40.9 (21.3; 78.6) 32 22 54.1 (35.6; 82.1)
ART & CD4 group CD4≥200 8* 3 17.0 (5.5; 52.7)
CD4 50–199, no Art 18 12 76.5 (43.4; 130)
CD4 50–199, ART 7 1 4.9 (0.68; 34.5)
CD4<50, no ART 21 20 194 (120; 300)
CD4<50. ART 8 3 15.1 (4.9; 46.7)
Adherence Almost/fully 15 2 6.4 (1.6; 25.4) 36 23 40.0 (26.6; 60.2)
Missed half 5 0 0 12 6 29.9 (13.4; 66.6)
No Info 12 9 114 (59.2; 218) 16 12 122 (69.1; 214)

* This is a time varying covariate; numbers are those for whom the category was their final category