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. 2014 Mar 6;9(3):e90500. doi: 10.1371/journal.pone.0090500

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© 2014 Bao, Schild

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a,b) The interaction of Ru(II) complexes with DNA (same as in in Fig. 1) shows double exponential decay([12], data courtesy of F. Secco, Univ Pisa,I). Same data fitted in t- (a) and L-domain (b). (c) Probability for the fitting error in the L-domain, , to be smaller than that in the t-domain, , represented as a function of and . Color code of the probability is shown beneath the plot. For each pair () 1000 trials were computed. (d) Relative difference of fitting errors, , as a function of and . Color code beneath the plot. 1000 trials per pixel. Left of the solid and dashed white lines in a and b, the success rate of the fit in the L-domain is larger that and , respectively. Left of the solid and dashed black lines in c and d, the success rate of the fit in the t-domain is larger that 50% and 95%, respectively. Relative error differences were calculated only for successful trials. (e) Success rate of fitting in the L-domain (solid) and t-domain (dashed) along the vertical line in c, i.e., as a function of with kept at .

Inline graphic — (a,b) The interaction of Ru(II) complexes with DNA (same as in in Fig. 1) shows double exponential decay([12], data courtesy of F. Secco, Univ Pisa,I). Same data fitted in t- (a) and L-domain (b). (c) Probability for the fitting error in the L-domain, , to be smaller than that in the t-domain, , represented as a function of and . Color code of the probability is shown beneath the plot. For each pair () 1000 trials were computed. (d) Relative difference of fitting errors, , as a function of and . Color code beneath the plot. 1000 trials per pixel. Left of the solid and dashed white lines in a and b, the success rate of the fit in the L-domain is larger that and , respectively. Left of the solid and dashed black lines in c and d, the success rate of the fit in the t-domain is larger that 50% and 95%, respectively. Relative error differences were calculated only for successful trials. (e) Success rate of fitting in the L-domain (solid) and t-domain (dashed) along the vertical line in c, i.e., as a function of with kept at .