Table 2.
List of plants possibly working as inhibitors of lipid droplets synthesis or as promoter of lypolysis
Species name (family name) |
Plant parts used | Bioactive anti-LDA fraction(s) or compound(s) | Mechanism of action | Ref. no. |
---|---|---|---|---|
Bergenia crassifolia (L.) Fritsch. (Saxifragaceae) | Root | 3,11-di-O-galloylbergenin, 4,11-di-O-galloylbergenin | Not reported | [128] |
Citrus sunki Hort. ex. Tanaka. (Rutaceae) | Fruit Peel | Ethanol extract | Activation of AMPK and ACC inhibitor | [129] |
Elsholtzia ciliata (Thunb.) Hyl. (Lamiaceae) | Whole | Ethanol extract | Inhibition of expression of PPARγ, and subsequently FAS and aP2 | [130] |
Galega officinalis (L.) (Fabaceae) | Whole | Galegine | ACC inhibitor | [131] |
Nelumbo nucifera Gaertn. (Nelumbonaceae) | Leaf and Seed | Ethanol extract | Inhibition of expression of FAS and SREBP-1c and acting as ACC inhibitor, and down-regulater of PPARγ | [132–136] |
Nepeta japonica Maximowicz (Lamiaceae) | Whole | Ethanol extract | Inhibition of pancreatic lipase activity | [137] |
Peucedanum japonicum Thunb. (Apiaceae) | Leaf and Stem | Ethanol extract | Increase of expression of ATGL | [138–141] |
Sasa quelpaertensis Nakai. (Poaceae) | Leaf | p-coumaric acid | Activation of AMPK leading to increase in fatty acid oxidation activity | [142–145] |
Zingiber mioga Rosc. (Zingiberaceae) | Shoot | Ethanol extract | Reduction TG and G3PDH whose exact mechanism is not yet elucidated | [146] |