Table 3.
Univariate and multivariate analysis of pre-operative and histological factors affecting 1-year recurrence after resection of hepatic colorectal metastases in 65 patients
| Factor (n = 65) | Univariate P-value | Multivariate P-value | Incidence ratio (95% CI) |
|---|---|---|---|
| Age | 0.025a | 0.876 | |
| Gender | 0.506 | ||
| Max diameter of tumour at histology | 0.323 | ||
| Number of lesions | 0.240a | 0.831 | |
| Capsule smooth and intact | 0.408 | ||
| Margin less than 1 mm | 0.109a | 0.045b | 2.89 (1.61– 5.18) |
| Margin less than 10 mm | 0.545 | ||
| Histological response to chemotherapy | 0.674 | ||
| T stage of primary tumour | 0.571 | ||
| N stage of primary tumour | 0.381 | ||
| Synchronous versus metachronous | 0.824 | ||
| Liver directed chemotherapy (yes/no) | 0.710 | ||
| Neutrophil lymphocyte ratio (>5) | 0.320 | ||
| Pseudocapsule present | 0.114a | 0.030b | 0.30 (0.174–0.524) |
| Necrosis of largest lesion | 0.886 |
a
Significant at the level of 0.25 for univariate analysis and included in multivariate analysis.
b
Significant at the level of 0.05 for multivariate analysis.