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Ion fluxes are indicated by arrows. The lower magnification represents the different components of the uniporter complex. MCU Oligomerization at IMM forms a tetramer (shadowed subunits). MCUb is represented as the black shadowed subunit. SERCA, sarcoendoplasmic reticulum calcium transport ATPase; VDAC, voltage-dependent anion channel; TMD, transmembrane domain; RuR, Ruthenium Red. See text for further details.
