Figure 9.

A–C, time course of mean arterial pressure (MAP) in mice in the low K⁺ (A, 0.03% K⁺, 3% Na⁺; n = 4), normal K⁺ (B, 0.93% K⁺, 3% Na⁺; n = 4) and high K⁺ (C, 5% K⁺, 3% Na⁺; n = 6) groups treated with hydrochlorothiazide (HCTZ) (14.3 mg kg⁻¹ per day) compared with MAP in mice on the control diet (0.93% K⁺, 0.24% Na⁺). D–F, MAP_night in mice on the control diet in comparison with MAP_night in mice treated with HCTZ and the experimental diets (mean ± s.e.m; **P < 0.01, Student's paired t test). Blood pressure recordings were performed for 48 h before the experimental diets were started and again in the same mice at the end of the experimental period.