Table 1. Upregulated CXC-type chemokine genes in the lateral wall of 3-NP-injured cochlea.
Receptor and its cell types | Chemokine Ligands | Day1 | Day3 |
CXCR2 (not detected) | CXCL1 | 7 | 2.9 |
neutrophils | CXCL2 | 3.5 | 2.2 |
monocytes | CXCL3 | NC | NC |
CXCL5 | NC | NC | |
CXCR3 (not detected) | CXCL9 | 8.2 | 4.1 |
various cell types | CXCL10 | 6.5 | NC |
CXCL11 | 6.3 | NC | |
CXCR4 | CXCL12 | 2 | NC |
widely expressed | |||
CX3CR1 | CX3CL1 | NC | NC |
macrophages |
The values displayed refer to the -fold changes compared with the saline-treated controls.
Genes showing >2-fold changes are listed.
NC: no change compared with control.