Table 2.

Depressed Mood Scores and Severity As Assessed by the BDI-II in Cohort 1 and the CES-D in Cohort 2 and MDASI Individual Mood-Related Items

Item	Cohort 1 (n = 187)			Cohort 2 (n = 281)
Depressed-mood category*
None to minimal
No.	128			220
%	68.4			78.3
Mild
No.	34			36
%	18.2			12.8
Moderate to severe
No.	25			25
%	13.4			8.9

	Mean	SD	Range	Mean	SD	Range
Depressed-mood component score†	11.2	7.9	0-36	10.7	9.3	0-45
MDASI mood-related item scores
Sadness	2.2	3.1	0-10	1.3	2.1	0-9
Distress	2.2	2.9	0-10	1.5	2.2	0-9
Fatigue	3.4	2.9	0-10	3.0	2.1	0-10
Interference with enjoyment of life	3.2	3.4	0-10	1.6	2.5	0-10
Interference with mood	2.3	2.8	0-10	1.4	2.1	0-10
Interference with relations with others	1.4	2.4	0-10	1.1	2.0	0-10

Abbreviations: BDI-II, Beck Depression Inventory-II; CES-D, Center for Epidemiologic Studies Depression Scale; MDASI, MD Anderson Symptom Inventory; SD, standard deviation.

^*For cohort 1: BDI-II score < 14 = minimal depressed mood; 14 to 19 = mild depressed mood; ≥ 20 = moderate-to-severe depressed mood. For cohort 2: CES-D score < 16 = no or minimal depressed mood; 16 to 26 = mild depressed mood; ≥ 27 = moderate-to-severe depressed mood.

^†Depressed-mood component score = sum score of MDASI sadness, fatigue, interference with mood, relations with others, and enjoyment of life.