Figure 3. Knockdown of HYAL2 or CD44 impairs tubulogenesis.

TIME cells were transfected with scrambled control siRNA or siRNAs for HYAL2 or CD44 for 24 h, before seeded onto Matrigel. Phase contrast overview photos, using a Zeiss Axiovert40 microscope, were taken at the indicated time points. A representative experiment out of three experiments performed in duplicates is depicted. Scale bar, 200 µm.