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. 2014 Mar 10;9(3):e90921. doi: 10.1371/journal.pone.0090921

Figure 6. Effect of CD44 knockdown on the Erk MAPK pathway and NFκB target genes.

Figure 6

Endothelial cells transfected with scrambled control siRNA or siRNA against CD44 were grown under differentiating or proliferating conditions and subjected to SDS-PAGE followed by immunoblotting for Cleaved Caspase 3 and the phosphorylated and total versions of proteins known to be involved in the Erk- and p38 MAPK-signaling, as well as STAT3, FAK and NFκB signaling. A representative experiment out of four experiments performed with similar results is shown ± SD.