Table 6. Treatment response and adverse drug reaction.
| No or mild ADR n, (%) | Severe ADR n, (%) | p value | |
| Adherence to antiretroviral therapy | |||
| Optimally adherent 1 patients at 6 months | 187 (85.5%) | 59 (73.8%) | 0.02* |
| Optimally adherent patients at 12 months | 180 (90.9%) | 69 (93.3%) | 0.61 |
| Optimally adherent patients at 24 months | 173 (91.5%) | 62 (85.7%) | 0.16 |
| Virological response | |||
| Viral failure 2 at 6 months | 25 (10.1%) | 10 (11.5%) | 0.94 |
| Viral failure at 12 months | 22 (12.1%) | 15 (11.1%) | 0.12 |
| Viral failure at 24 months | 35 (12.3%) | 17 (10.5%) | 0.33 |
| Immunological response | |||
| CD4>350 at 6 months | 73 (39.1%) | 37 (45%) | 0.06 |
| CD4>350 at 12 months | 82 (49.6%) | 34 (44.7%) | 0.39 |
| CD4>350 at 24 months | 99 (61.3%) | 41 (68.3%) | 0.23 |
*significant difference seen.
1
Optimally adherent: adherence >95%.
2
Viral failure: viral load >400 copies/ml.