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. 2014 Jan 6;196(3):781–797. doi: 10.1534/genetics.113.160945

Figure 4.

Figure 4

Larval expression pattern of neprilysin genes. (A–D) Expression of Nep1–4 in larval CNS. (A) Nep1 in mushroom bodies (mb), pars intercerebralis (pi), and ventral ganglia (vg). (B) Nep2 in few cells in the brain (br) and in the ventral ganglia (vg). (C) Nep3 in central brain (cbr) and thoracic ventral ganglia (tvg). (D) Nep4 in glia of the larval CNS. (E–H) Expression of Nep1–3 in the larval gastrointestinal system. (E) Nep1 in cells in the midgut. (F–G) Nep2 in the proventriculus (pv) and in the stellate cells of the Malpighian tubules (arrowheads). (H) Nep3 in scattered cells in the larval midgut (arrowheads). (I–L) Expression of Nep1 and Nep2 in larval imaginal discs. (I) Nep1 in leg disc. (J) Nep1 in dorsal and ventral wing pouch (dwp–vwp) and ventral pleura (vp) of the wing disc. (K) Nep2 in the eye disc anterior (arrowhead) to the morphogenetic furrow (mf) and in the second antennal segment (arrow). (L) Nep2 in the leg disc femur (fe) and tarsus (ta).