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. 2014 Mar 10;9(3):e91370. doi: 10.1371/journal.pone.0091370

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© 2014 Korrer, Routes

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

Mice were injected with PBS or 1×10⁵ live MCA-205-OVA or MCA-205-E1A-OVA tumor cells s.c. in the flank three times, five days apart. Five days after last tumor dose (day 20), mice were challenged with 1×10⁴ MCA-205-OVA tumor cells on the contralateral flank. Mice were administered two injections of 10 μg of anti-CD3 or control IgG before and after MCA-205-OVA tumor challenge on days 17, 19, 22 and 24. Survival curves show the percentage of mice without tumor from MCA-205-OVA cell challenge only. Data was analyzed by the log-rank (Mantel Cox) test. **, p<.01; ***, p<.001.