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. 2014 Mar 10;9(3):e91307. doi: 10.1371/journal.pone.0091307

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© 2014 Wang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A, C) Representative pictures of migration and invasion assays in SGC7901 and MKN28 cells (magnification 200×) are shown. (B, D) The migrated cells were counted by choosing five fields of each chamber randomly and calculating the average number. Our results showed that LV3-hsa-miR-214 transfection markedly decrease the migration and invasion ability of SGC7901 (P = 0.0143 and 0.0210, respectively). While knockdown of miR-214 with miR-214 inhibitor promotes cellular migration (P = 0.0491) and invasion (P = 0.0127) in MKN28 cells.