Fig. 5.

The livers of +/Dsk5 mice have elevated cholesterol esters but decreased phospholipids and triglycerides. A: RNA, DNA, and protein were measured in the +/+ and +/Dsk5 mice using the TRI Reagent. The values were referenced to the wet weight of the tissue. No significant differences were found for these molecules. B: Phospholipid (PL), triglyceride (TG), and cholesterol ester (CE) concentrations were measured in pieces of liver obtained from the +/+ or +/Dsk5 mice and expressed relative to the wet weight. There is increased CE in the liver of the +/Dsk5 mice compared with the +/+ mice but decreased PL and TG. *P < 0.02; **P < 0.001.