Table 2.

Serum chemistry in wild-type and Ostα^−/− mice

	5 Months		12 Months
	Wild-type	Ostα−/−	Wild-type	Ostα−/−
	Male
Total cholesterol, mg/dl	55 ± 5	54 ± 3	66 ± 3#	63 ± 3
HDL, mg/dl	57 ± 4	50 ± 5	65 ± 2	62 ± 4
LDL, mg/dl	6.9 ± 0.4	5.6 ± 0.8	7.1 ± 0.5	6.9 ± 0.5
Triglycerides, mg/dl	41 ± 6	40 ± 7	42 ± 4	42 ± 7
Free fatty acids, μM	951 ± 91	785 ± 94	865 ± 61	821 ± 28
Bile acids, μM	35 ± 8	29 ± 6	30 ± 2	38 ± 3
	Female
Total cholesterol, mg/dl	62 ± 5	59 ± 3	61 ± 2	62 ± 2
HDL, mg/dl	44 ± 2	43 ± 1	41 ± 1	41 ± 2
LDL, mg/dl	13 ± 0.7	12 ± 1	11.1 ± 0.4	10.1 ± 0.9
Triglycerides, mg/dl	47 ± 6	58 ± 5	40 ± 2	45 ± 3
Free fatty acids, μM	830 ± 74	999 ± 98	725 ± 70	822 ± 72
Bile acids, μM	5.1 ± 0.4	9.5 ± 0.7*	6.0 ± 0.8	5.5 ± 0.6#

Values are means ± SE (n = 4–14). Serum from overnight-fasted animals was analyzed.

^*P < 0.05 vs. wild-type.

^#P < 0.05 vs. 5 mo.