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Inhibition of Src-family protein tyrosine kinase (SFK) abolished the effect of ANG II on the 50-pS K channel. A bar graph summarizes the experiments in which the effect of ANG II (50 nM) on the 50-pS K channels in the TAL was examined in the presence or in the absence of 1 μM herbimycin A or 4-amino-5-(4-methyphenyl)-7-(t-buty)-pyrazolo[3,4-d]-pyrimidine (PP1). All experiments were performed in cell-attached patches. *Significant difference from the rest of the groups.
