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Effects of ROCK inhibition on afferent arteriolar diameters in ANG II-infused rats. After establishing steady-state diameters, ANG II (1 nmol/l) was superfused on the blood vessels. Afferent arteriolar responses to fasudil superfusion from 1 to 100 μmol/l were evaluated in control rats (⧫; n = 6) and chronic ANG II infused rats (●; n = 5). Values are means ± SE. *P < 0.05 vs. Δ% at 10 min. #P < 0.05 vs. Δ% of control.
