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. 2013 Dec 27;306(5):L405–L419. doi: 10.1152/ajplung.00143.2013

Fig. 1.

Fig. 1.

GRHL2 is abundantly expressed in the developing lung epithelium but only appears in lung mesenchyme at week 9. Double staining of Grhl2 and its target E-cadherin (CDH1) in embryonic lung tissue (A–C), fetal lung tissue (D–F), and normal adult lung tissue (G and H). C′, F′, and I′ are insets. C″, F″, and I″ are enlarged regions of the small box shown in C, F, and I, respectively. Blue arrows show airway epithelium. Open white arrows show mesenchyme and white arrows show epithelium. Double staining of GRHL2 and alveolar type II epithelial cell marker ABCA3 in fetal lung tissue (J–L) and normal adult lung tissue (M–O). L′ and O′ are insets. Insets do not show DAPI for clarity. Scale is 100 μm for A–O, 20 μm for C′, F′, I′, L′, and O′, and 10 μm for C″, F″, and I″.