Table 2.

Maximal contractile responses and pEC₅₀ of Eln^+/+ and Eln^+/− mesenteric arteries to ANG II in the absence or presence of the selective ANG type 2 receptor blocker PD-123319

	ANG II		ANG II + PD-123319
	Eln+/+	Eln+/−	Eln+/+	Eln+/−
No. of arteries	10	8	5	5
Maximal contractile response, %	36 ± 4	59 ± 5†	39 ± 5	53 ± 7
pEC50	8.1 ± 0.1	8.7 ± 0.1*	7.9 ± 0.2	8.2 ± 0.1‡

Data are means ± SE. pEC₅₀, sensitivity.

^*P < 0.05 and

^†P < 0.01 vs. Eln^+/+;

^‡P < 0.05 vs. Eln^+/− in the absence of PD-123319.