Table 3.

pEC₅₀ values of Eln^+/+ and Eln^+/− mesenteric arteries to ANG II and PE in the presence or absence of the Rho kinase inhibitor Y-27632

	ANG II		PE
	Eln+/+	Eln+/−	Eln+/+	Eln+/−
No. of arteries	4–10	5–8	5–7	5–8
Y-27632
0 μmol/l	8.0 ± 0.2	8.6 ± 0.1*	5.7 ± 0.1	5.6 ± 0.2
0.1 μmol/l	8.1 ± 0.1	8.1 ± 0.2	5.6 ± 0.6	6.2 ± 0.2
1 μmol/l	8.5 ± 0.5	7.9 ± 0.2†	5.6 ± 0.1	6.1 ± 0.2
5 μmol/l	ND	7.4 ± 0.3†	5.0 ± 0.6	5.7 ± 0.1

Data are means ± SE. PE, phenylephrine; ND, not determined.

^*P < 0.05 vs. Eln^+/+;

^†P < 0.01 vs. Eln^+/− in the absence of Y-27632.