Table 1.
NIDCM Patients | Control Subjects | P Value | |
---|---|---|---|
No. of subjects | 61 | 61 | |
Sex, no. of subjects | 0.4 | ||
Men | 33 | 38 | |
Women | 28 | 23 | |
Age, yr | 56 ± 12 | 58 ± 13 | 0.4 |
Heart rate, beats/min | 66 ± 13 | 64 ± 13 | 0.4 |
QRS duration > 120 ms | |||
No. of subjects | 31 | 0 | |
Percent | 51 | 0 | |
LV chamber | |||
End-diastolic volume, ml | 163 ± 77 | 84 ± 22 | <0.0001 |
End-systolic volume, ml | 122 ± 71 | 31 ± 9 | <0.0001 |
Stroke volume, ml | 41 ± 15 | 53 ± 15 | <0.0001 |
Ejection fraction | 0.27 ± 0.09 | 0.63 ± 0.05 | <0.0001 |
LV mass, g | 215 ± 73 | 129 ± 35 | <0.0001 |
Long-axis diastolic diameter, cm | 9.2 ± 1.1 | 8.3 ± 0.8 | <0.0001 |
Short-axis diastolic diameter, cm | 6.0 ± 1.0 | 4.5 ± 0.5 | <0.0001 |
Sphericity index | 0.7 ± 0.1 | 0.5 ± 0.1 | <0.0001 |
Vortex formation time | 1.43 ± 0.83 | 3.95 ± 1.78 | <0.0001 |
Conventional Doppler | |||
Mitral regurgitation III–IV/IV | |||
No. of subjects | 22 | 0 | |
Percent | 36 | 0 | |
Isovolumic relaxation time, ms | 117 ± 37 | 94 ± 25 | 0.002 |
E wave velocity, m/s | 0.65 ± 0.23 | 0.66 ± 0.14 | 0.79 |
A wave velocity, m/s | 0.67 ± 0.23 | 0.64 ± 0.18 | 0.32 |
E/A | 1.07 ± 0.67 | 1.13 ± 0.46 | 0.57 |
E wave deceleration time, ms | 163 ± 52 | 198 ± 52 | 0.0003 |
e′ wave velocity, m/s | 0.06 ± 0.02 | 0.10 ± 0.03 | <0.0001 |
E/e′ | 13 ± 6 | 7 ± 2 | <0.0001 |
Diastolic intraventricular pressure gradients | |||
Total early DIVPD, mmHg | 1.1 ± 0.4 | 1.1 ± 0.6 | 0.78 |
Inertial early DIVPD, mmHg | 1.5 ± 0.5 | 1.6 ± 0.6 | 0.65 |
Convective early DIVPD, mmHg | −1.3 ± 0.7 | −1.0 ± 0.6 | 0.02 |
Late DIVPD, mmHg | 1.4 ± 0.5 | 0.7 ± 0.5 | <0.0001 |
NIDCM, nonischemic dilated cardiomyopathy; LV, left ventricular; DIVPD, diastolic intraventricular pressure difference.