Table 1.

Acute effects of cadmium on 30-min apical uptake of 10 μM [³H]choline in cultured choroid plexus epithelial cells

Cadmium Concentration, nM	[3H]Choline Uptake, pmol·mg protein−1·30 min−1
0 (Control)	2928.8 ± 264.1
50	3121.7 ± 174.0
100	3008.9 ± 280.5
250	3030.8 ± 232.8
500	2947.2 ± 211.0
1,000	2923.9 ± 200.1

Values are expressed as means ± SE, using triplicate measures; n = 3 culture preparations. Choroid plexus cells were plated on impermeable supports and exposed to cadmium only during the transport assay. Cells were incubated at 37°C for 30 min in artificial cerebrospinal fluid (10 mM Tris-HEPES, pH 7.4) with 10 μM [³H]choline chloride and 0–1000 nM cadmium chloride. At the tested concentrations, cadmium did not alter choline uptake; P > 0.62 vs. control uptake in the absence of cadmium.