Table 3.
Top 10 genes induced (ozone/air >1) by subacute ozone exposure and with significantly different expression in ozone exposed WT and Adipo−/− mice
| Affymetrix ID | Genes Induced by Ozone | Gene Symbol | Log2 Ozone-Air WT | Log2 Ozone-Air Adipo−/− |
|---|---|---|---|---|
| 1450826_a_at | serum amyloid A 3 | Saa3 | 1.56 | 3.99 |
| 1421074_at, 1421075_s_at | cytochrome P-450, family 7, subfamily b, polypeptide 1 | Cyp7b1 | 0.58, 0.72 | 1.57, 1.2 |
| 1460227_at | tissue inhibitor of metalloproteinase 1 | Timp1 | 3.0 | 3.79 |
| 1452242_at | centrosomal protein 55 | Cep55 | 2.15 | 2.79 |
| 1429295_s_at | thyroid hormone receptor interactor 13 | Trip13 | 0.87 | 1.49 |
| 1437716_x_at | kinesin family member 22 | Kif22 | 1.34 | 1.89 |
| 1419513_a_at | ect2 oncogene | Ect2 | 1.97 | 2.47 |
| 1433893_s_at | sperm associated antigen 5 | Spag5 | 0.65 | 1.15 |
| 1449227_at | cholesterol 25-hydroxylase | Ch25 h | 0.63 | 1.12 |
| 1422462_at | ubiquitin-conjugating enzyme E2T | Ube2t | 0.7 | 1.19 |
Adipo−/−, adiponectin deficient.