Table 4.
Top 10 genes reduced (ozone/air <1) by subacute ozone exposure and with significantly different expression in ozone exposed WT and Adipo−/− mice
| Affymetrix ID | Genes Reduced by Ozone | Gene Symbol | Log2 Air-Ozone WT | Log2 Air-Ozone Adipo−/− |
|---|---|---|---|---|
| 1449434_at | carbonic anhydrase 3 | Car3 | 0.73 | 2.61 |
| 1451644_a_at 1431008_at | histocompatibility 2, Q region locus 1/6/7/8/9* | H2-Q1,6,7,8,9 | 1.5, 1.1 | 0.1, 0.2 |
| 1436898_at | splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | sfpq | 1.85 | 0.99 |
| 1417898_a_at | granzyme A | gzma | 1.1 | 0.24 |
| 1425329_a_at | cytochrome b5 reductase 3 | Cyb5r3 | 2.77 | 1.96 |
| 1427202_at | RIKEN cDNA 4833442J19 gene | 4833442J19Rik | 1.1 | 0.57 |
| 1450459_at | RIKEN cDNA 2010106G01 gene | 2010106G01Rik | 1.27 | 0.78 |
| 1423155_at | sorcin | sri | 1.17 | 0.7 |
| 1422411_s_at | eosinophil-associated, ribonuclease A family, member 1/2/3 | Ear1,ear2,ear3 | 1.31 | 0.87 |
| 1452125_at | thyroid hormone receptor associated protein 3 | Thrap3 | 1.15 | 0.74 |
Change in gene expression values are organized by the magnitude of the difference in the ozone induced change in Adipo−/− versus WT mice.
*
This Affy ID is included in each of these histocompatibility 2, Q region locus genes.