Table 5.
Top 15 cluster categories (by enrichment score) of genes significantly different in Adipo−/− versus WT mice exposed to air
| Cluster Category | Enrichment Score | Gene Count | P Value |
|---|---|---|---|
| Extracellular matrix | 3.25 | 10 | 1.4E-4 |
| Cell migration | 2.96 | 10 | 3.9E-4 |
| Polysaccharide binding | 1.98 | 6 | 7.2E-3 |
| Extracellular matrix structural component | 1.97 | 5 | 1.7E-4 |
| Positive regulation of cell-substrate adhesion | 1.95 | 4 | 1.9E-3 |
| Regulation of body fluid levels | 1.61 | 5 | 9.4E-3 |
| Monovalent inorganic cation homeostasis | 1.6 | 5 | 4.1E-4 |
| Hemopoiesis | 1.37 | 7 | 2.9E-2 |
| Neural crest cell differentiation | 1.25 | 3 | 3.7E-2 |
| Respiratory system development | 1.23 | 5 | 2.8E-2 |
Functional annotation clustering was performed by using the program DAVID on high stringency.