Table 1.
Proteins identified in unstimulated (CNTL) and ATP stimulated H292 cells.
| Protein name | Accession number | M.W. (kDa) |
No. of peptides |
||
|---|---|---|---|---|---|
| CNTL | ATP | ||||
| 1 | Cluster of Uncharacterized protein (IPI00022434) | ||||
| 1.1 | Uncharacterized protein | IPI00022434 | 72 | 8 | 6 |
| 1.2 | Uncharacterized protein | IPI00878517 | 56 | 6 | 4 |
| 2 | Cluster of Isoform DPI of Desmoplakin (IPI00013933) | ||||
| 2.1 | Isoform DPI of Desmoplakin | IPI00013933 | 332 | 12 | 13 |
| 2.2 | Desmoplakin Ia | IPI00969616 | 279 | 10 | 12 |
| 2.3 | cDNA FLJ61543, highly similar to Desmoplakin | IPI01009332 | 156 | 9 | 8 |
| 2.4 | CDNA FLJ26719 fis, clone PNC03379 | IPI00746877 | 20 | 0 | 0 |
| 3 | Desmoglein-1 | IPI00025753 | 114 | 5 | 10 |
| 4 | Cluster of actin, cytoplasmic 1 (IPI00021439) | ||||
| 4.1 | Actin, cytoplasmic 1 | IPI00021439 (+1) | 42 | 4 | 7 |
| 4.2 | Isoform 1 of POTE ankyrin domain family member E | IPI00479743 | 121 | 2 | 2 |
| 4.3 | Putative beta-actin-like protein 3 | IPI00888712 | 42 | 0 | 0 |
| 4.4 | POTE ankyrin domain family member I | IPI00740545 | 121 | 0 | 0 |
| 4.5 | cDNA FLJ52761, highly similar to Actin, aortic smooth muscle | IPI00984879 | 37 | 2 | 0 |
| 4.6 | POTE ankyrin domain family member J | IPI00738655 | 117 | 0 | 0 |
| 4.7 | Actin, alpha skeletal muscle | IPI00021428 | 42 | 3 | 3 |
| 4.8 | POTE ankyrin domain family member F | IPI00739539 | 121 | 2 | 2 |
| 4.9 | Uncharacterized protein | IPI00645534 | 17 | 2 | 2 |
| 4.10 | cDNA FLJ52755, highly similar to Actin, aortic smooth muscle | IPI00921887 | 17 | 2 | 2 |
| 4.11 | Uncharacterized protein | IPI00917820 | 16 | 2 | 2 |
| 4.12 | Uncharacterized protein | IPI00917545 | 6 | 0 | 0 |
| 4.13 | Actin-like protein (Fragment) | IPI00970910 | 11 | 0 | 0 |
| 4.14 | Similar to Kappa-actin | IPI00893501 | 5 | 0 | 0 |
| 4.15 | Actin-like protein (Fragment) | IPI00970912 | 12 | 0 | 0 |
| 4.16 | Uncharacterized protein | IPI00917282 | 11 | 0 | 0 |
| 5 | Cluster of Heat shock protein HSP 90-beta (IPI00414676) | ||||
| 5.1 | Heat shock protein HSP 90-beta | IPI00414676 | 83 | 5 | 9 |
| 5.2 | Heat shock protein 90Bb | IPI00455599 | 49 | 0 | 3 |
| 5.3 | Isoform 2 of Heat shock protein HSP 90-alpha | IPI00382470 (+1) | 98 | 0 | 9 |
| 5.4 | Putative heat shock protein HSP 90-beta 4 | IPI00555565 | 58 | 0 | 2 |
| 5.5 | Putative heat shock protein HSP 90-alpha A2 | IPI00031523 | 39 | 0 | 3 |
| 5.6 | Uncharacterized protein | IPI00604607 | 49 | 0 | 7 |
| 5.7 | Uncharacterized protein | IPI00514027 | 19 | 0 | 0 |
| 6 | Junction plakoglobin | IPI00554711 | 82 | 5 | 9 |
| 7 | Cluster of Isoform 2 of Filamin-A (IPI00302592) | ||||
| 7.1 | Isoform 2 of Filamin-A | IPI00302592 (+2) | 280 | 0 | 8 |
| 7.2 | Protein | IPI00893150 | 10 | 0 | 0 |
| 7.3 | Filamin A, alpha | IPI01018650 | 25 | 0 | 0 |
| 8 | Cluster of cDNA FLJ56442, highly similar to ATP-citrate synthase (IPI00394838) | ||||
| 8.1 | cDNA FLJ56442, highly similar to ATP-citrate synthase | IPI00394838 | 125 | 5 | 15 |
| 8.2 | ATP-citrate synthase | IPI00021290 | 121 | 5 | 15 |
| 9 | Hornerin | IPI00398625 | 282 | 7 | 3 |
| 10 | Cluster of Glyceraldehyde-3-phosphate dehydrogenase (IPI00219018) | ||||
| 10.1 | Glyceraldehyde-3-phosphate dehydrogenase | IPI00219018 | 36 | 3 | 4 |
| 10.2 | Glyceraldehyde-3-phosphate dehydrogenase | IPI00795257 | 32 | 3 | 4 |
| 10.3 | Glyceraldehyde-3-phosphate dehydrogenase | IPI00789134 | 28 | 2 | 3 |
| 11 | Cluster of Isoform 1 of Myosin-9 (IPI00019502) | ||||
| 11.1 | Isoform 1 of Myosin-9 | IPI00019502 | 227 | 6 | 13 |
| 11.2 | FLJ00279 protein (Fragment) | IPI00742780 | 66 | 3 | 3 |
| 11.3 | Uncharacterized protein | IPI00556012 | 25 | 0 | 0 |
| 12 | Cluster of Isoform 2 of Annexin A2 (IPI00418169) | ||||
| 12.1 | Isoform 2 of Annexin A2 | IPI00418169 | 40 | 4 | 4 |
| 12.2 | Putative annexin A2-like protein | IPI00334627 | 39 | 3 | 3 |
| 12.3 | cDNA FLJ34687 fis, clone MESAN2000620, highly similar to Annexin A2 | IPI00903334 | 21 | 2 | 2 |
| 13 | Filaggrin-2 | IPI00397801 | 248 | 5 | 2 |
| 14 | Cluster of 88 kDa protein (IPI01026194) | ||||
| 14.1 | 88 kDa protein | IPI01026194 | 88 | 0 | 0 |
| 14.2 | Uncharacterized protein | IPI00645452 (+4) | 48 | 0 | 4 |
| 14.3 | Similar to Tubulin beta-2A chain | IPI00975573 | 24 | 0 | 0 |
| 14.4 | TUBB6 protein | IPI00646779 | 50 | 0 | 0 |
| 14.5 | Tubulin beta-8 chain B | IPI00174849 | 50 | 0 | 0 |
| 14.6 | Tubulin beta-4 chain | IPI00023598 | 50 | 0 | 2 |
| 14.7 | Putative uncharacterized protein (Fragment) | IPI00827736 | 17 | 0 | 0 |
| 14.8 | Tubulin beta 2C (Fragment) | IPI00956734 | 10 | 0 | 0 |
| 14.9 | Putative tubulin beta-4q chain | IPI00018511 | 48 | 0 | 0 |
| 15 | Cluster of Hemoglobin subunit beta (IPI00654755) | ||||
| 15.1 | Hemoglobin subunit beta | IPI00654755 (+1) | 16 | 0 | 4 |
| 15.2 | Hbbm fused globin protein (Fragment) | IPI00930351 | 11 | 0 | 2 |
| 15.3 | Hemoglobin subunit gamma-2 | IPI00554676 | 16 | 0 | 0 |
| 15.4 | Hemoglobin subunit epsilon | IPI00217471 | 16 | 0 | 0 |
| 16 | Dermcidin | IPI00027547 | 11 | 3 | 3 |
| 17 | Cluster of Uncharacterized protein (IPI01015738) | ||||
| 17.1 | Uncharacterized protein | IPI01015738 | 80 | 0 | 3 |
| 17.2 | alpha-actinin-1 isoform a | IPI00759776 | 106 | 0 | 4 |
| 17.3 | cDNA FLJ54718, highly similar to Alpha-actinin-1 | IPI01025172 | 30 | 0 | 0 |
| 17.4 | 34 kDa protein | IPI01009456 | 34 | 0 | 2 |
| 17.5 | Protein | IPI01026210 | 29 | 2 | |
| 18 | Cluster of 268 kDa protein (IPI00942045) | ||||
| 18.1 | 268 kDa protein | IPI00942045 | 268 | 0 | 7 |
| 18.2 | Uncharacterized protein | IPI01014477 | 120 | 0 | 5 |
| 18.3 | Isoform 4 of Acetyl-CoA carboxylase 1 | IPI00396015 | 270 | 0 | 7 |
| 19 | Cluster of Trifunctional enzyme subunit alpha, mitochondrial (IPI00031522) | ||||
| 19.1 | Trifunctional enzyme subunit alpha, mitochondrial | IPI00031522 | 83 | 2 | 5 |
| 19.2 | cDNA FLJ52806, highly similar to Trifunctional enzyme subunit alpha, mitochondrial | IPI00908351 | 28 | 0 | 0 |
| 20 | Cluster of Pyruvate carboxylase, mitochondrial (IPI00299402) | ||||
| 20.1 | Pyruvate carboxylase, mitochondrial | IPI00299402 | 130 | 0 | 5 |
| 20.2 | Uncharacterized protein | IPI00975989 | 33 | 0 | 5 |
| 21 | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial | IPI00024580 | 80 | 0 | 4 |
| 22 | myosin-11 isoform SM1B | IPI00743857 | 228 | 0 | 2 |
| 23 | Cluster of Uncharacterized protein (IPI00922694) | ||||
| 23.1 | Uncharacterized protein | IPI00922694 | 70 | 0 | 4 |
| 23.2 | Stress-70 protein, mitochondrial | IPI00007765 (+1) | 74a | 0 | 4 |
| 24 | Cluster of Annexin A1 (IPI00218918) | ||||
| 24.1 | Annexin A1 | IPI00218918 | 39 | 0 | 5 |
| 24.2 | Uncharacterized protein | IPI00549413 | 23 | 0 | 0 |
| 25 | 30 kDa protein | IPI00917420 | 30 | 3 | 2 |
| 26 | Fatty acid synthase | IPI00026781 | 273 | 0 | 2 |
| 27 | Cluster of Protein (IPI01012384) | ||||
| 27.1 | Protein | IPI01012384 | 124 | 0 | 3 |
| 27.2 | Importin 5 | IPI00514205 | 14 | 0 | 0 |
| 27.3 | Uncharacterized protein | IPI00947399 | 14 | 0 | 0 |
| 28 | Isoform 2 of Plakophilin-1 | IPI00071509 (+1) | 83 | 2 | 2 |
| 29 | Cluster of T-complex protein 1 subunit beta (IPI00297779) | ||||
| 29.1 | T-complex protein 1 subunit beta | IPI00297779 | 57 | 0 | 2 |
| 29.2 | T-complex protein 1 subunit beta isoform 2 | IPI00981169 | 53 | 0 | 0 |
| 30 | Cluster of Puromycin-sensitive aminopeptidase (IPI00026216) | ||||
| 30.1 | Puromycin-sensitive aminopeptidase | IPI00026216 | 103 | 2 | 2 |
| 30.2 | Protein | IPI00979097 | 49 | 0 | 0 |
| 30.3 | Uncharacterized protein | IPI00976960 | 22 | 0 | 0 |
| 30.4 | Uncharacterized protein | IPI00984113 | 20 | 0 | 0 |
| 31 | Isoform 2 of Propionyl-CoA carboxylase alpha chain, mitochondrial | IPI00895869 | 77 | 0 | 4 |
| 32 | Cluster of Uncharacterized protein (IPI00964079) | ||||
| 32.1 | Uncharacterized protein | IPI00964079 | 57 | 0 | 2 |
| 32.2 | cDNA FLJ59103, highly similar to T-complex protein 1 subunit epsilon | IPI00909956 | 32 | 0 | 2 |
| 33 | Cluster of Isoform 1 of Myosin-14 (IPI00337335) | ||||
| 33.1 | Isoform 1 of Myosin-14 | IPI00337335 (+3) | 228 | 0 | 2 |
| 33.2 | Isoform 5 of Myosin-14 | IPI00029818 (+1) | 168 | 0 | 0 |
| 34 | Cluster of tropomyosin alpha-3 chain isoform 1 (IPI00183968) | ||||
| 34.1 | tropomyosin alpha-3 chain isoform 1 | IPI00183968 | 33 | 0 | 2 |
| 34.2 | TPM1 protein variant (Fragment) | IPI00940084 | 34 | 0 | 0 |
| 34.3 | tropomyosin alpha-1 chain isoform 7 | IPI00216134 | 33 | 0 | 0 |
| 34.4 | Isoform 2 of Tropomyosin alpha-4 chain | IPI00216975 | 33 | 0 | 0 |
| 34.5 | cDNA FLJ16459 fis, clone BRCAN2002473, moderately similar to Tropomyosin, fibroblast isoform 2 | IPI00940343 | 37 | 0 | 0 |
| 34.6 | Isoform 2 of Tropomyosin beta chain | IPI00220709 | 33 | 0 | 0 |
| 34.7 | Isoform 1 of Tropomyosin alpha-4 chain | IPI00010779 | 29 | 0 | 0 |
| 34.8 | Isoform 1 of Tropomyosin beta chain | IPI00013991 | 33 | 0 | 0 |
| 34.9 | Uncharacterized protein | IPI01018017 | 28 | 0 | 0 |
| 35 | Cluster of cDNA FLJ53765, highly similar to Tubulin alpha chain (IPI00909762) | ||||
| 35.1 | cDNA FLJ53765, highly similar to Tubulin alpha chain | IPI00909762 | 20 | 0 | 3 |
| 35.2 | cDNA FLJ55956, highly similar to Tubulin alpha-6 chain | IPI00387144 | 58 | 0 | 4 |
| 35.3 | cDNA FLJ53743, highly similar to Tubulin alpha-3 chain | IPI00936821 | 43 | 0 | 0 |
| 35.4 | Tubulin alpha-4A chain | IPI00007750 (+1) | 50 | 0 | 2 |
| 35.5 | Tubulin alpha-3E chain | IPI00410402 | 50 | 0 | 2 |
| 35.6 | Isoform 1 of Tubulin alpha-3C/D chain | IPI00179709 | 50 | 0 | 2 |
| 35.7 | Isoform 2 of Tubulin alpha-3C/D chain | IPI00218345 | 46 | 0 | 2 |
| 35.8 | Similar to Tubulin alpha-3C/D chain | IPI00784332 | 36 | 0 | 0 |
| 35.9 | Uncharacterized protein | IPI01022794 | 25 | 0 | 0 |
| 36 | Isoform 2 of Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | IPI00337495 | 87 | 0 | 4 |
| 37 | Isoform 1 of Myosin-10 | IPI00397526 (+1) | 229 | 0 | 2 |
| 38 | Exportin-1 | IPI00298961 | 123 | 0 | 2 |
| 39 | Ubiquitin-like modifier-activating enzyme 1 | IPI00645078 | 118 | 0 | 2 |
| 40 | Cluster of Elongation factor 2 (IPI00186290) | ||||
| 40.1 | Elongation factor 2 | IPI00186290 | 95 | 0 | 2 |
| 40.2 | Uncharacterized protein | IPI01010856 | 65 | 0 | 0 |
| 41 | Cluster of ADP/ATP translocase 3 (IPI00291467) | ||||
| 41.1 | ADP/ATP translocase 3 | IPI00291467 | 33 | 0 | 0 |
| 41.2 | ADP/ATP translocase 4 | IPI00010420 | 35 | 0 | 0 |
| 41.3 | ADP/ATP translocase 2 | IPI00007188 | 33 | 0 | 2 |
| 42 | Uncharacterized protein | IPI00943181 | 29 | 0 | 3 |
| 43 | Isoform 1 of Clathrin heavy chain 1 | IPI00024067 (+1) | 192 | 0 | 3 |
| 44 | Cluster of Elongation factor 1-alpha 1 (IPI00396485) | ||||
| 44.1 | Elongation factor 1-alpha 1 | IPI00396485 | 50 | 2 | 0 |
| 44.2 | Putative elongation factor 1-alpha-like 3 | IPI00472724 | 50 | 2 | 0 |
| 44.3 | Elongation factor 1-alpha 2 | IPI00014424 | 50 | 2 | 0 |
| 44.4 | EEF1A protein (Fragment) | IPI00382804 | 24 | 0 | 0 |
| 45 | Cluster of Alpha-amylase 1 (IPI00300786) | ||||
| 45.1 | Alpha-amylase 1 | IPI00300786 (+1) | 58 | 3 | 0 |
| 45.2 | 58 kDa protein | IPI00646265 | 58 | 3 | 0 |
| 46 | Beta-actin-like protein 2 | IPI00003269 | 42 | 0 | 2 |
| 47 | Isoform 1 of Glycerol-3-phosphate dehydrogenase, mitochondrial | IPI00017895 | 81 | 0 | 2 |
| 48 | Cluster of cDNA FLJ56389, highly similar to Elongation factor 1-gamma (IPI00000875) | ||||
| 48.1 | cDNA FLJ56389, highly similar to Elongation factor 1-gamma | IPI00000875 (+1) | 56 | 0 | 2 |
| 48.2 | cDNA FLJ59433, highly similar to Elongation factor 1-gamma | IPI00909534 | 24 | 0 | 0 |
| 49 | Isoform 1 of Arginase-1 | IPI00291560 (+1) | 35 | 0 | 2 |
| 50 | cDNA FLJ60461, highly similar to Peroxiredoxin-2 | IPI00909207 | 20 | 0 | 2 |
| 51 | Cluster of Peroxiredoxin-4 (IPI00011937) | ||||
| 51.1 | Peroxiredoxin-4 | IPI00011937 | 31 | 0 | 3 |
| 51.2 | Protein | IPI00639945 | 18 | 0 | 3 |
| 52 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor | IPI00025874 | 73 | 0 | 4 |
| 53 | triosephosphate isomerase isoform 2 | IPI00465028 (+1) | 31 | 0 | 2 |
| 54 | Transferrin receptor protein 1 | IPI00022462 | 85 | 0 | 2 |
| 55 | Transitional endoplasmic reticulum ATPase | IPI00022774 | 89 | 0 | 2 |
| 56 | CTP synthase 1 | IPI00290142 | 67 | 0 | 2 |
| 57 | Isoform 1 of F-actin-capping protein subunit beta | IPI00026185 (+1) | 31 | 0 | 2 |
| 58 | Cluster of Isoform 2 of Inactive tyrosine-protein kinase 7 (IPI00170814) | ||||
| 58.1 | Isoform 2 of Inactive tyrosine-protein kinase 7 | IPI00170814 (+2) | 114 | 0 | 2 |
| 58.2 | PTK7 protein tyrosine kinase 7 isoform a variant (Fragment) | IPI00555762 | 84 | 0 | 0 |
| 58.3 | Uncharacterized protein | IPI00946128 | 29 | 0 | 0 |
| 59 | Cluster of Importin-7 (IPI00007402) | ||||
| 59.1 | Importin-7 | IPI00007402 | 120 | 0 | 2 |
| 59.2 | Uncharacterized protein | IPI00981775 | 15 | 0 | 0 |
| 60 | Cluster of Isoform 2 of Voltage-dependent anion-selective channel protein 3 (IPI00294779) | ||||
| 60.1 | Isoform 2 of Voltage-dependent anion-selective channel protein 3 | IPI00294779 | 31 | 0 | 2 |
| 60.2 | Uncharacterized protein | IPI00981487 | 18 | 0 | 0 |
| 61 | cDNA FLJ39276 fis, clone OCBBF2010843, highly similar to Guanine nucleotide-binding protein G(i), alpha-2 subunit | IPI00925504 | 39 | 0 | 2 |
| 62 | Isoform 3 of Tropomyosin alpha-3 chain | IPI00218320 (+1) | 29 | 0 | 2 |
| 63 | Conserved hypothetical protein | IPI00978107 | 22 | 0 | 2 |
One of the protein members in the cluster is assigned by Scaffold to represent the corresponding cluster.