Table 1.
Subject characteristics and clinical chemistries.
| Vitamin D status |
||||
|---|---|---|---|---|
| Deficient | Insufficient | Sufficient | p-value | |
| n (males:females) | 17 (9:8) | 21 (9:12) | 18 (7:11) | |
| Age (y) | 51±3 | 48±2 | 47±3 | 0.536 |
| Height (cm) | 167±2 | 170±2 | 168±2 | 0.487 |
| Body mass (kg) | 100.6±5.4 | 99.7±4.6 | 81.4±3.3a,b | 0.006 |
| BMI (kg/m2) | 36.0±1.8 | 34.2±1.3 | 28.6±0.8a,b | 0.001 |
| Serum 25(OH)D (ng/ml) | 16.3±0.7 | 24.7±0.6a | 36.0±0.8a,b | <0.001 |
| Rheumatoid factor (IU/ml) | 9.18±0.46 | 8.95±0.44 | 8.83±0.45 | 0.599 |
| iPTH (pg/mL) | 50.1±3.8 | 44.1±3.6 | 33.6±2.2a,c | 0.004 |
| Calcium (mg/dL) | 9.35±0.13 | 9.29±0.1 | 9.49±0.10 | 0.632 |
| WOMAC pain (0–20) | 9.47±1.03 | 7.60±0.63 | 6.69±0.82 | 0.320 |
| WOMAC function (0–68) | 30.1±3.4 | 24.7±2.4 | 19.7±2.5 | 0.461 |
| Kellgren–Lawrence grade | 0.468 | |||
| 2 (n) | 1 | 4 | 0 | |
| 3 (n) | 14 | 9 | 15 | |
| 4 (n) | 2 | 8 | 3 | |
Data presented as mean±SEM unless otherwise noted.
All subjects were Caucasian.
a
p<0.05 vs. deficient.
b
p<0.05 vs. insufficient.
c
p=0.07 vs. insufficient.