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Formation of AGEs via Wolff'-, Namiki- and Hodge-pathway. Autoxidation of monosaccharides or carbonyl compounds (Wolff' pathway), aldimins (Namiki-pathway) or Amadori products (Hodge-pathway) via transition metals or ROS can lead directly to the formation of RCCs and in further reaction to AGEs (modified from [3], [17], [38], [39], [40]).
