Table 1.
Weekly analysis of blood glucose levels, OGTT measurement at day 26, HbA1c blood levels, triglyceride blood levels, insulin blood levels and NEFAs blood levels at day 28.
| Parameter | Saline (Zucker) | CB3, 1 mg/kg | CB3, 10 mg/kg | Rosi, 10 mg/kg |
|---|---|---|---|---|
| HbA1c (%) | 7.24±0.56 | 7.49±0.51 | 9.54±0.85 | 4.56±0.05* |
| Triglyceride (mg/dl) | 873.5±51.4 | 881.7±40.7 | 1065.0±147.8 | 112.4±7.07* |
| NEFAs (mEq/L) | 0.61±0.06 | 0.58±0.06 | 0.47±0.08 | 0.14±0.03* |
| Insulin (ng/ml) | 13.5±2.9 | 18.6±2.9 | 13.4±2.6 | 6.5±2.1 |
| MCP-1 (pg/ml) | 6845±587 | 5532±834 | 5361±786 | 5307±874 |
The values shown are the averages (±SEM) of all animals in each group. Student's t-test (two populations) was performed for ZDF rats treated with saline only (Zucker).
⁎
P value<0.05; (n=4–8).