Table 6.

Impact of rosiglitazone on heart and cardiomyocyte growth in heart muscle in late gestation

Heart and Cardiomyocyte Measures	Control	Rosiglitazone
Absolute heart weight, g/kg	32.9 ± 1.4	34.0 ± 1.9
Relative heart weight, g/kg	7.1 ± 0.3	6.9 ± 0.2
Percentage of mononucleated cardiomyocytes, %	50.5 ± 1.4	54.1 ± 4.0
Mononucleated cardiomyocyte length, mm	60.3 ± 1.7	53.2 ± 1.0*
Mononucleated cardiomyocyte width, mm	10.0 ± 0.6	10.8 ± 0.4
Binucleated cardiomyocyte length, mm	77.7 ± 2.3	68.0 ± 1.2*
Binucleatedcardiomyocyte width, mm	10.8 ± 0.6	11.6 ± 0.4

Data are presented as means ± SE.

^*P < 0.05.