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. 2014 Mar 11;5:27. doi: 10.3389/fneur.2014.00027

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Copyright © 2014 Bonnan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fraction of intrathecal Ig secretion in various disorders. Disease-related Ig secretion is minor even in infectious disorders (See Ref. in text). Intrathecal synthesis is mostly dominated by non-specific synthesis, including an MRZH pattern, which represents a minor proportion. Disease-related secretion in MS and MRZH patterns in infections are as yet unknown.