. Author manuscript; available in PMC: 2015 May 15.

Published in final edited form as: Int J Cancer. 2013 Nov 18;134(10):2278–2283. doi: 10.1002/ijc.28575

Table 2.

Urinary levels of total NNN and total NNAL in relation to risk of lung cancer, The Shanghai Cohort Study 1986–2007

	1^st tertile	2^nd tertile	3^rd tertile	P for trend
Total NNN (fmol/mg Cr)	<40.9	40.9–70.7	>70.7
Cases/controls	24/31	29/33	40/29
Matched OR (95% CI)^*	1.00	1.19 (0.59–2.37)	1.99 (0.91–4.35)	0.087
Adjusted OR (95% CI)^†	1.00	0.82 (0.36–1.88)	1.02 (0.39–2.69)	0.958
NNAL-adjusted OR (95% CI)^‡	1.00	0.50 (0.19–1.35)	0.47 (0.13–1.64)	0.271
Total NNAL (pmol/mg Cr)	<0.14	0.14–0.29	>0.29
Cases/controls	15/31	34/33	44/29
Matched OR (95% CI)^*	1.00	2.44 (1.05–5.67)	4.23 (1.66–10.80)	0.003
NNN-adjusted OR (95% CI)^§	1.00	1.95 (0.63–6.07)	4.29 (0.96–19.23)	0.053

Matched odds ratios were derived from conditional logistic regression models that controlled for age, year and month of sample collection, and neighborhood of residence at enrollment.

^†

Adjusted for number of cigarettes per day, number of years of smoking, urinary total cotinine, and urinary PheT.

^‡

Adjusted for number of cigarettes per day, number of years of smoking, urinary total cotinine, urinary PheT, and urinary total NNAL.

^§

Adjusted for number of cigarettes per day, number of years of smoking, urinary total cotinine, urinary PheT, and urinary total NNN.