Figure 1. Radiotherapy of Colon38 tumors results in responders and non-responders.
1×105 Colon38 tumor cells were injected i.m. in the left thigh and either treated with 15 Gy radiation seven days later or left unirradiated. Tumor size was measured with calipers and presented as means +/- SE (A) or individual tumor measurement from irradiated animals only (B). A digital picture showing representative tumor burdens is illustrated in (C). The tumor bearing leg is designated with an arrow. Mice that responded to radiation had tumor measurements at day 11 that were smaller than day 9 tumor measurements and vice-versa for non-responder tumors. * denotes a significant difference between non-responder and responder tumor size based on t-test (p < 0.05) at that particular timepoint. n=6 for unirradiated tumors and 12 for irradiated tumors (6 responders and 6 non-responders).