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. Author manuscript; available in PMC: 2014 Mar 12.
Published in final edited form as: J Pharm Sci. 2011 Jun 6;100(10):4171–4197. doi: 10.1002/jps.22618

Figure 3.

Figure 3

An illustration of three types of spaces, using simulated data. In Figure (A), four pH values define a one dimensional search grid in search space, and ratios of secondary structure type illustrate a protein phase space. Figure (B) shows how two measurement types define a measurement phase space. The transition pH values disagree when we plot measurements separately, as in Figures (C) and (D). A plot in measurement phase space (B) synthesizes the information, but will not work as a visual aid for high dimensional data.