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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Gene Ther. 2014 Jan 16;21(3):289–297. doi: 10.1038/gt.2013.84

Table 1. Hematology and chemistry values in 4T1 bearing mice treated with MV-m-uPA*.

TEST Treatment Normal range Units of Measure
Ctrl (vehicle) MV-m-uPA
White Blood Cell Count 16.37±3.27 24.57 ±7.40 4.5-9.1 ×103/ul
Red Blood Cell Count 9.93±0.37 9.95±0.23 7.51-9.66 ×106/ul
Hemoglobin 14.53±0.25 14.77±0.50 12.8-16.1 g/dL
Hematocrit 46.67.±1.15 46±2.65 34-50 %
MCV 46.67±0.58 46±1.73 41-60 fL
MCH 14.67±0.58 14.67±0.58 13-19 pg
MCHC 31.33±0.58 32.3±1.15 30-39 %
Segmented Neutrophis 64±2.65 71.33±2.31 21-57 %
Band Neutrophils 0±0 0±0 0-1 %
Lymphocytes 32.67±3.06 23±3.61 49-82 %
Monocytes 0.67±0.58 1.67±0.58 2-8 %
Eosinophils 2.33±0.58 4±1 0-3 %
Basophils 0.33±0.58 0 0-3 %
NRBC 0±0 0
RBC Morphology Normal Normal
Platelet Morphology Normal Normal
WBC Morphology Normal Normal
Hemolysis 2 ±0 1.67±0.58 0
Lipemia Index 0±0 0±0 0
Glucose 161.67±54.24 145±55.82 90-193 mg/dL
BUN 15.33±1.15 13.67.±1.52 18-29 mg/dL
CREA 0.1±0 0.13±0.06 0.1-0.4 mg/dL
Calcium 8.6±0.6 9.33±0.42 8.7-10.1 mg/dL
Phosphorus 9.37±0.25 8.63±0.47 5.4-9.3 mg/dL
Total Protein 5.2±0.1 5.4±0.53 4.6-6.9 g/dL
ALT 99.67±10.01 54.67±13.2 29-191 U/L
*

4T1 tumor bearing Balb/c mice (n = 5) were given 2 doses of 1.5×106 MV-m-uPA or PBS via tail vein as described in the methods section At day 5, blood samples were obtained for complete blood count and clinical chemistry (liver and renal function) analysis using a Hemavet 1700 multispecies hematology analyzer and an Ortho Vitros 250 analyzer, respectively.