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. 2014 Mar 11;4:4347. doi: 10.1038/srep04347

Table 3. Connection of glycosylation features related to fucosylation, sialylation and bisecting GlcNAc with measures of severity of inflammatory response (highest CRP, number of leukocytes, number of trombocytes).

Glycan feature Phenotype R R2 p p adjusted
FG0n total/G0n max CRP −0.393 0.155 <0.001 0.003
Fn total max CRP −0.361 0.131 0.001 0.006
FG1n total/G1n max CRP −0.336 0.113 0.002 0.010
FBS total/FS total thrombocytes −0.264 0.070 0.010 0.042
FS/S max CRP −0.277 0.077 0.010 0.042
FG2n total/G2n max CRP −0.228 0.052 0.034 0.119
S leukocytes 0.192 0.037 0.061 0.181
S max CRP 0.153 0.023 0.158 0.415
FG0n total/G0n thrombocytes 0.085 0.007 0.412 0.888
FS/S thrombocytes 0.084 0.007 0.423 0.888
ΔFG0n total/G0n max CRP 0.390 0.152 0.000 0.003
ΔFG1n total/G1n max CRP 0.270 0.073 0.011 0.081
ΔFS/S max CRP 0.264 0.070 0.014 0.081
ΔFG2n total/G2n max CRP 0.211 0.045 0.050 0.224
ΔS leukocytes −0.165 0.027 0.109 0.392
ΔFG1n total/G1n thrombocytes 0.151 0.023 0.148 0.443
ΔFBStotal/FStotal thrombocytes 0.140 0.020 0.177 0.456
ΔFG2n total/G2n leukocytes −0.107 0.012 0.299 0.539
ΔFG0n total/G0n thrombocytes 0.112 0.013 0.283 0.539
ΔS max CRP −0.125 0.016 0.248 0.539

FG0n/G0n - the percentage of fucosylation of agalactosylated structures without bisecting GlcNAc;

Fn total - the percentage of all fucosylated structures in total neutral glycan fraction;

FG1n total/G1n - the percentage of fucosylation of monogalactosylated structures;

FBS total/FS total - ratio of all fucosylated sialylated structures with and without bisecting GlcNAc;

FS/S – level of fucosylation of sialylated structures;

FG2n total/G2n - the percentage of fucosylation of digalactosylated structures;

S – the percentage of sialylated structures;

FG0n total/G0 - the percentage of fucosylation of agalactosylated structures;

Δindicates the difference between day 0 and day 1.