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. 2013 Dec 11;111(6):1259–1273. doi: 10.1152/jn.00941.2012

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Fig. 7. — LFS at low current intensities and paired-pulse LFS fail to induce LTD at LPP-DG and MPP-DG synapses in pentobarbital-anesthetized rats. A: normalized LPP-DG fEPSP dV/dt analysis (means ± SE) demonstrate no LTD following 900 pulse, 1-Hz LPP LFS delivered at stimulation intensities evoking 25% of the maximal fEPSP response in pentobarbital-anesthetized rats (n = 6). Inset: responses calibration: 0.5 mV, 5 ms. B: normalized MPP-DG fEPSP dV/dt analysis (means ± SE) reveal no change in baseline MPP-DG fEPSPs following 900 pulse, 1-Hz MPP LFS delivered at stimulation intensities producing 25% of the maximal fEPSP response in pentobarbital-anesthetized rats (n = 5). Inset: calibration: 0.5 mV, 5 ms. C: normalized LPP-DG fEPSP dV/dt analysis (means ± SE) depicting the induction of a rapid onset LTP following LPP paired-pulse LFS (900 paired pulses, 200 ms interpulse interval) in pentobarbital-anesthetized rats (n = 4). Inset: calibration: 1 mV, 5 ms. D: normalized MPP-DG fEPSP dV/dt analysis (means ± SE) demonstrate slow onset LTP following MPP paired-pulse LFS (900 paired pulses, 200-ms interpulse interval) in pentobarbital-anesthetized rats (n = 5). Inset: response calibration: 1 mV, 5 ms.