Table 2.
Biochemical Thyroid Indices in 375 Childbearing-Aged Women in Lubumbashi, Democratic Republic of Congo
| All maternity units | TSH, mIU/L | FT4, ng/dL | FT3, pg/mL | Tg, ng/mL | TPOAb positive |
|---|---|---|---|---|---|
| All pregnant (n=225) | 1.80 (1.13–2.63) | 0.85 (0.67–1.00) | 1.44 (1.01–2.23) | 13.3 (4.7–23.2) | 12 (5.3) |
| 1st trimester (n=76) | 1.54 (0.82–2.12) | 0.80 (0.55–0.99) | 1.56 (0.81–2.75) | 9.2 (3.0–16.4) | 7 (9.2) |
| 2nd trimester (n=71) | 1.99 (1.28–2.78) | 0.86 (0.71–0.98) | 1.41 (1.09–2.00) | 14.3 (5.3–23.7) | 5 (7.0) |
| 3rd trimester (n=78) | 2.06 (1.34–2.83) | 0.86 (0.68–1.04) | 1.52 (1.07–1.98) | 15.9 (7.4–25.5) | 0 (0.0) |
| p-valuea | 0.005 | 0.24 | 0.78 | 0.01 | 0.02 |
| Postpartum (n=75) | 2.80 (1.75–3.78) | 1.11 (0.94–1.45) | 0.91 (0.60–1.60) | 11.8 (8.0–15.1) | 10 (13.3) |
| Nonpregnant (n=75) | 1.54 (1.11–2.98) | 1.16 (0.79–1.38) | 1.71 (1.28–2.37) | 11.8 (8.5–15.6) | 3 (4.0) |
| p-valueb | <0.001 | <0.001 | <0.001 | 0.01 | 0.03 |
Data are medians with quartiles in parentheses, and number and percentages in parentheses for TPOAb positive.
a
Comparison between trimesters of gestation.
b
Comparison between pregnant, postpartum, and nonpregnant women.
FT3, free triiodothyronine; FT4, free thyroxine; Tg, thyroglobulin; TPOAb, antithyroperoxidase antibody; TSH, thyrotropin.