Table 3.
Biochemical Thyroid Indices of 375 Women in Lubumbashi, Democratic Republic of Congo, According to Socioeconomic Area
| TSH, mIU/L | FT4, ng/dL | FT3, pg/mL | Tg, ng/mL | TPOAb positive | |
|---|---|---|---|---|---|
| Rural area | |||||
| All pregnant (n=75) | 1.99 (1.30–2.81) | 0.81 (0.69–0.92) | 1.46 (1.09–2.19) | 15.4 (6.4–24.6) | 0 (0.0) |
| T1 (n=25) | 1.70 (0.89–2.50) | 0.99 (0.88–1.15) | 1.61 (0.94–2.19) | 11.3 (6.4–21.0) | 0 (0.0) |
| T2 (n=25) | 2.07 (1.26–2.79) | 0.78 (0.69–0.82) | 1.57 (1.15–2.28) | 14.3 (7.4–27.4) | 0 (0.0) |
| T3 (n=25) | 2.40 (1.73–2.96) | 0.73 (0.68–0.82) | 1.22 (1.04–1.67) | 18.7 (4.8–27.4) | 0 (0.0) |
| p-valuea | 0.19 | <0.001 | 0.27 | 0.57 | |
| Postpartum (n=25) | 2.51 (1.69–3.08) | 1.45 (1.04–1.58) | 1.61 (0.54–2.11) | 9.8 (7.2–12.7) | 0 (0.0) |
| Nonpregnant (n=25) | 1.71 (0.69–3.29) | 0.98 (0.66–1.22) | 1.64 (0.57–2.36) | 11.4 (8.5–16.5) | 1 (4.0) |
| p-valueb | 0.001 | <0.001 | 0.78 | 0.002 | |
| Semiurban area | |||||
| All pregnant (n=75) | 2.10 (1.15–3.38) | 0.95 (0.62–1.11) | 2.11 (1.42–3.22) | 12.0 (5.8–18.7) | 9 (12.0) |
| T1 (n=26) | 1.05 (0.33–1.75) | 0.58 (0.33–0.79) | 2.91 (1.06–3.79) | 6.2 (1.5–11.9) | 7 (26.9) |
| T2 (n=24) | 2.28 (1.41–3.34) | 0.98 (0.80–1.09) | 1.70 (1.33–2.29) | 14.3 (6.9–25.5) | 2 (8.3) |
| T3 (n=25) | 2.75 (2.14–4.26) | 1.10 (0.98–1.27) | 1.97 (1.61–2.78) | 14.2 (10.5–19.5) | 0 (0.0) |
| p-valuea | <0.001 | <0.001 | 0.10 | 0.002 | |
| Postpartum (n=25) | 3.73 (2.64–5.25) | 1.09 (0.95–1.49) | 0.67 (0.54–0.93) | 11.9 (7.9–17.0) | 1 (4.0) |
| Nonpregnant (n=25) | 2.26 (1.78–3.88) | 1.38 (1.32–1.48) | 2.25 (1.63–2.61) | 9.4 (6.9–15.1) | 1 (4.0) |
| p-valueb | <0.001 | <0.001 | <0.001 | 0.01 | |
| Urban area | |||||
| All pregnant (n=75) | 1.43 (0.97–2.14) | 0.84 (0.60–0.96) | 1.10 (0.71–1.43) | 12.3 (0.0–23.8) | 3 (4.0) |
| T1 (n=25) | 1.86 (1.15–2.59) | 0.76 (0.58–0.91) | 1.05 (0.67–1.55) | 10.1 (1.9–18.3) | 0 (0.0) |
| T2 (n=22) | 1.43 (1.16–2.03) | 0.89 (0.74–0.96) | 1.09 (0.75–1.33) | 14.5 (0.0–22.6) | 3 (13.6) |
| T3 (n=28) | 1.27 (0.81–2.02) | 0.80 (0.51–0.96) | 1.15 (0.83–1.69) | 16.4 (0.0–36.3) | 0 (0.0) |
| p-valuea | 0.17 | 0.34 | 0.68 | 0.35 | |
| Postpartum (n=25) | 2.08 (1.05–3.34) | 1.05 (0.78–1.12) | 1.06 (0.74–1.52) | 11.9 (8.0–15.4) | 9 (36.0) |
| Nonpregnant (n=25) | 1.72 (1.08–2.60) | 1.02 (0.65–1.23) | 1.60 (1.32–1.88) | 11.9 (9.5–15.6) | 1 (4.0) |
| p-valueb | 0.14 | 0.009 | <0.001 | 0.83 | |
Data are medians with quartiles in parentheses, and number and percentages in parentheses for TPOAb positive.
a
Comparison between trimesters of gestation.
b
Comparison between pregnant, postpartum, and nonpregnant women.
T1, 1st trimester; T2, 2nd trimester; T3, 3rd trimester.