Table 5.
Factors Associated with a High Serum Thyrotropin Level Using Logistic Regression
| Univariate | Multivariate | ||||||
|---|---|---|---|---|---|---|---|
| n (%) | Odds ratio | 95% confidence interval | p | Odds ratio | 95% confidence interval | p | |
| Socioeconomic area | <0.001 | <0.001 | |||||
| Rural | 22 (17.6) | 1.59 | [0.77–3.29] | 1.55 | [0.74–3.26] | ||
| Semiurban | 40 (32.0) | 3.58 | [1.82–7.03] | 3.68 | [1.85–7.35] | ||
| Urban | 14 (11.2) | 1 | 1 | ||||
| Group | 0.004 | 0.01 | |||||
| Pregnancy | 48 (21.3) | 3.03 | [1.24–7.43] | 3.43 | [1.23–9.53] | ||
| Postpartum | 21 (28.0) | 4.34 | [1.64–11.52] | 4.49 | [1.66–15.01] | ||
| Control | 7 (9.3) | 1 | 1 | ||||
| UIC, μg/L | 0.01 | 0.02 | |||||
| <150 | 37 (24.0) | 0.90 | [0.49–1.68] | 1.11 | [0.55–2.25] | ||
| 150–249 | 21 (25.9) | 1 | 1 | ||||
| ≥250 | 16 (12.0) | 0.39 | [0.19–0.80] | 0.44 | [0.19–0.96] | ||
| TPOAb status | 0.97 | ||||||
| Positive | 5 (20.0) | 0.98 | [0.36–2.71] | ||||
| Negative | 71 (20.3) | ||||||
| Parity | 0.27 | 0.05 | |||||
| 0–1 | 24 (24.2) | 1 | 1 | ||||
| 2 or plus | 52 (18.8) | 0.73 | [0.42–1.28] | 0.49 | [0.23–1.02] | ||
| Age, years | 0.19 | ||||||
| <25 | 35 (23.8) | 1 | |||||
| ≥25 | 41 (18.1) | 0.71 | [0.43–1.18] | ||||
A high serum TSH: >3 mIU/L in 2nd and 3rd trimester, >2.5 mIU/L in 1st trimester, >3.6 mIU/L in early postpartum, and >4.0 mIU/L in nonpregnant women. Bold values are statistically significant odds ratios.