Table 1.
Histopathological Scoring of Thyroid Lesions in BRAFV600E/TshR+/− and BRAFV600E/TshR−/− Mice
Overall process | Cellular features | |||||
---|---|---|---|---|---|---|
Genotype | Age (weeks) | Neoplastic | Nuclear changes | Tall cells | Solid pattern | Capsular invasion |
BRAFV600E/TshR+/− | 12 | 9/10 | 9/10 | 3/10 | 2/10 | 2/10 |
24 | 10/10 | 9/10 | 4/10 | 4/10 | 3/10 | |
BRAFV600E/TshR−/− | 12 | 8/9 | 7/9 | 3/9 | 0/9 | 0/9 |
24 | 9/10 | 8/10 | 5/10 | 3/10 | 0/10 |